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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
17.88
Human Site:
T180
Identified Species:
24.58
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
T180
I
E
A
F
K
N
Y
T
L
D
S
S
A
A
P
Chimpanzee
Pan troglodytes
XP_522180
647
68973
T180
I
E
A
F
K
N
Y
T
L
D
S
S
A
A
P
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
T180
I
E
A
F
K
N
Y
T
L
D
S
S
P
A
P
Dog
Lupus familis
XP_546524
647
68802
T180
I
E
A
F
K
N
Y
T
L
D
S
S
A
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
T179
I
E
A
F
K
N
Y
T
L
D
L
A
A
A
A
Rat
Rattus norvegicus
P08461
632
67147
Y170
D
I
E
A
F
K
N
Y
T
L
D
S
A
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
P86
P
P
A
P
P
A
P
P
P
P
S
A
A
A
P
Chicken
Gallus gallus
XP_417933
681
72018
L209
D
A
F
K
N
Y
T
L
D
S
A
A
S
A
P
Frog
Xenopus laevis
NP_001082239
628
66845
F157
K
A
E
F
I
D
A
F
K
N
Y
T
L
D
S
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
F180
L
I
S
S
F
K
D
F
T
L
D
K
I
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
V64
L
N
T
S
Q
S
P
V
T
W
S
Y
N
F
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
A59
A
R
Q
Y
P
N
A
A
A
F
S
I
K
Q
V
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
C39
L
Y
Q
L
Q
K
P
C
R
F
Y
S
S
E
D
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
H64
D
F
A
C
S
Q
V
H
W
K
R
G
F
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
E91
G
R
P
I
F
G
K
E
F
S
C
L
M
Q
S
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
H34
C
Y
A
S
Y
P
E
H
T
I
I
G
M
P
A
Red Bread Mold
Neurospora crassa
P20285
458
48601
A10
V
P
V
L
S
R
Q
A
L
R
H
A
S
V
A
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
93.3
100
N.A.
80
13.3
N.A.
33.3
13.3
6.6
0
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
13.3
N.A.
40
33.3
26.6
13.3
N.A.
26.6
N.A.
20
26.6
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
6.6
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
13.3
N.A.
N.A.
0
6.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
12
48
6
0
6
12
12
6
0
6
24
36
42
30
% A
% Cys:
6
0
0
6
0
0
0
6
0
0
6
0
0
0
0
% C
% Asp:
18
0
0
0
0
6
6
0
6
30
12
0
0
6
6
% D
% Glu:
0
30
12
0
0
0
6
6
0
0
0
0
0
6
0
% E
% Phe:
0
6
6
36
18
0
0
12
6
12
0
0
6
6
0
% F
% Gly:
6
0
0
0
0
6
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
12
0
0
6
0
0
0
0
% H
% Ile:
30
12
0
6
6
0
0
0
0
6
6
6
6
0
0
% I
% Lys:
6
0
0
6
30
18
6
0
6
6
0
6
6
0
0
% K
% Leu:
18
0
0
12
0
0
0
6
36
12
6
6
6
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
6
0
0
6
36
6
0
0
6
0
0
6
0
0
% N
% Pro:
6
12
6
6
12
6
18
6
6
6
0
0
6
6
36
% P
% Gln:
0
0
12
0
12
6
6
0
0
0
0
0
0
12
0
% Q
% Arg:
0
12
0
0
0
6
0
0
6
6
6
0
0
0
0
% R
% Ser:
0
0
6
18
12
6
0
0
0
12
42
36
18
6
24
% S
% Thr:
0
0
6
0
0
0
6
30
24
0
0
6
0
12
0
% T
% Val:
6
0
6
0
0
0
6
6
0
0
0
0
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
6
6
0
0
0
0
0
% W
% Tyr:
0
12
0
6
6
6
30
6
0
0
12
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _